Laboratory for
Precision Metabolomics and Exposomics (PRIME)
Instrumentation and Software
We use liquid chromatography and gas chromatography combined with high-resolution mass spectrometry for high-throughput, broad range, untargeted metabolite profiling. We have > 2000 compounds in our in-house library for unequivocal identification of endogenous and exogenous metabolites, and have developed software to help us link untargeted data to exposures and health
Research
Our laboratory's primary research focus is developing analytical tools for the discovery of biomarkers of disease and the effect of environmental factors (the exposome) on etiology and disease progression.
Technologies
In addition to urine, plasma, serum, and saliva we have developed novel technologies for untargeted analysis of archived neontatal dried blood spots (DBS), dried blood microsamplers, tissues, and teeth