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primary research


Metayer C, Imani P, Dudoit S, Morimoto L, Ma X, Wiemels JL, Petrick LM. One-Carbon (Folate) Metabolism Pathway at Birth and Risk of Childhood Acute Lymphoblastic Leukemia: A Biomarker Study in Newborns. Cancers (Basel). 2023 Feb 5;15(4):1011

India-Aldana S, Valvi D, Joshi A, Lucchini RG, Placidi D, Petrick L, Horton M, Niedzwiecki M, Colicino E. Salivary metabolomic signatures and body mass index (BMI) in Italian adolescents: a pilot study. Journal of the Endocrine Society. 2023 Jul 1:bvad091

Hua X, Ungaro RC, Petrick LM, Chan AT, Porter CK, Khalili H; Nurses’ Health Study; PREDICTS Collaborators. Inflammatory Bowel Disease Is Associated With Prediagnostic Perturbances in Metabolic Pathways. Gastroenterology. 2023 Jan;164(1):147-150.e2

L. Schmidt, K. Peterson, T.S. Nunes, M. Knap, L. Petrick, and J. Landero. A miniaturized sample preparation method for routine elemental determination in whole blood using volumetric absorptive microsampling by ICP-QQQ, Analytical and Bioanalytical Chemistry 2023 Aug 5

M. Pardo, C. Li, A. Jabali, L.M. Petrick, Z. Ben-Ari, Y. Rudich. The toxicity mechanisms of biomass burning aerosols on hepatic steatosis models in vitro. Science of the Total Environment. 2023 Dec 20 905

K. Davis, K, Knauft, L. Lewis, L. Rappaport, C.G., Engeland, H. Fritz, M. Cutchin, P. Levy, N. T. Joseph, M. Petriello, L. Petrick, F. Luca, S. Zilioli. The Heart of Detroit Study: A window into urban middle-aged and older African American’s daily lives to understand psychosocial determinants of cardiovascular disease risk. BMC Psychiatry. 23, Article number: 766 (2023)

M. van Gerwen, E. Colicino, H.Guan, G. Dolios, G.N. Nadkarni, R.CH Vermeulen, MS Wolff, M. Arora, E.M Genden, L.M Petrick. Per- and Polyfluoroalkyl Substances (PFAS) Exposure and Thyroid Cancer Risk,  eBioMedicine. Vol 97, 104831, 2023

Colicino E, Cowell W, Foppa Pedretti N, Joshi A, Petrick L, Niedzwiecki M, Wright RO, Wright RJ. Maternal steroids during pregnancy and their associations with exposure to lifetime stressful life events, prenatal stress appraisal and psychological functioning, Psychoneuroendocrinology, Vol 158, December 2023, 106395


Cowell W, Colicino E, Pedretti NF, Joshi, A, Youseff O, Just AC, Kloog I, Petrick LM, Niedzwiecki MM, Wright RO, Wright RJ. Maternal steroids during pregnancy and their associations with ambient air pollution and temperature during preconception and early gestational periods. Environment International. 2022 Jul;165:107320. doi: 10.1016/j.envint.2022.107320. Epub 2022 May 2516

Montag A,  Chambers C,  Jones K, Dassanayake P, Andra S, Petrick LM, Arora M, Austin C.
Prenatal alcohol exposure can be determined from baby teeth: proof of concept. Birth Defects Research. 2022 Jun 10. PMID: 3568668 doi: 10.1002/bdr2.2054


Yu M, Teitelbaum SL, Dolios G, Dang LT, Tu P, Wolff MS, Petrick LM. Molecular Gatekeeper Discovery: Workflow for Linking Multiple Exposure Biomarkers to Metabolomics. Environ Sci Technol. 2022 Feb 7. doi:10.1021/acs.est.1c04039. 


Yu M, Dolios G, Petrick LM. Reproducible untargeted metabolomics workflow for exhaustive MS2 data acquisition of MS1 features. J Cheminform. 2022 Feb 16;14(1):6. doi: 10.1186/s13321-022-00586-8.


Petrick LM, Wolff MS, Barupal D, Teitelbaum SL. Comparison of untargeted and targeted perfluoroalkyl acids measured in adolescent girls. Chemosphere. 2022 Mar; 290:133303.v doi: 10.1016/j.chemosphere.2021.133303. Epub 2021 Dec 15.

Haddad EN, Nel NH, Petrick LM, Kerver JM, Comstock SS. Associations between the Gut Microbiota, Urinary Metabolites, and Diet in Women during the Third Trimester of Pregnancy. Curr Dev Nutr. 2022 Dec 24;7(4):100025


Petrick L, Imani P, Perttula K, Yano Y, Whitehead T, Metayer C, Schiffman C, Dolios G, Dudoit S, Rappaport S. Untargeted metabolomics of newborn dried blood spots reveals sex-specific associations with pediatric acute myeloid leukemia. Leuk Res. 2021 Jul;106:106585. doi: 10.1016/j.leukres.2021.106585. Epub 2021 Apr 24.

Whitehead TP, Wiemels JL, Zhou M, Kang AY, McCoy LS, Wang R, Fitch B, Petrick LM, Yano Y, Imani P, Rappaport SM, Dahl GV, Kogan SC, Ma X, Metayer C. Cytokine levels at birth in children who developed acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev. 2021 Jun 2;. doi: 10.1158/1055-9965.EPI-20-1704.

Hu J, Lesseur C, Miao Y, Manservisi F, Panzacchi S, Mandrioli D, Belpoggi F, Chen J, Petrick L. Low-dose exposure of glyphosate-based herbicides disrupt the urine metabolome and its interaction with gut microbiota. Sci Rep. 2021 Feb 5;11(1):3265. doi: 10.1038/s41598-021-82552-2.

Niedzwiecki MM, Eggers S, Joshi A, Dolios G, Cantoral A, Lamadrid-Figueroa H, Amarasiriwardena C, Téllez-Rojo MM, Wright RO, Petrick L. Lead exposure and serum metabolite profiles in pregnant women in Mexico City. Environ. Health 2021 Dec 10;20(1):125. doi: 10.1186/s12940-021-00810-2

Lupo PJ, Petrick LM, Hoang TT, Janitz AE, Marcotte EL, Schraw JM, Arora M, Scheurer ME. Using primary teeth and archived dried spots for exposomic studies in children: Exploring new paths in the environmental epidemiology of pediatric cancer. Bioessays. 2021 Jun 9;:e2100030. doi: 10.1002/bies.202100030

van Gerwen M, Gold B, Alsen M, Khan MN, Petrick LM, Genden E. High Thyroid Cancer Incidence Rate in a Community near a Landfill: A Descriptive Epidemiological Assessment. Toxics. 2021 Dec 1;9(12):325. doi:10.3390/toxics9120325. PMID: 34941759

Yu M, Tu P, Dolios G, Dassanayake PS, Volk H, Newschaffer C, Fallin MD, Croen L, Lyall K, Schmidt R, Hertz-Piccioto I, Austin C, Arora M, Petrick LM.  Tooth biomarkers to characterize the temporal dynamics of the fetal and early-life exposome. Environ Int. 2021 Dec;157:106849. doi:10.1016/j.envint.2021.106849. Epub 2021 Sep 2.


Yu M, Dolios G, Yong-Gonzalez V, Björkqvist O, Colicino E, Halfvarson J, Petrick L. Untargeted metabolomics profiling and hemoglobin normalization for archived newborn dried blood spots from a refrigerated biorepository. J Pharm Biomed Anal. 2020 Nov 30;191:113574. doi: 10.1016/j.jpba.2020.113574. Epub 2020 Aug 23

Yu M, Petrick LM. Untargeted high-resolution paired mass distance data mining for retrieving general chemical relationships. Communications chemistry. 2020 November; 3(157).

Chetnik K, Petrick L, Pandey G. MetaClean: a machine learning-based classifier for reduced false positive peak detection in untargeted LC-MS metabolomics data. Metabolomics. 2020 Oct 21;16(11):117. doi: 10.1007/s11306-020-01738-3

Yano Y, Schiffman C, Grigoryan H, Hayes J, Edmands W, Petrick L, Whitehead T, Metayer C, Dudoit S, Rappaport S. Untargeted adductomics of newborn dried blood spots identifies modifications to human serum albumin associated with childhood leukemia. Leuk Res. 2020 Jan;88:106268. doi: 10.1016/j.leukres.2019.106268. Epub 2019 Nov 6


Petrick LM, Schiffman C, Edmands WMB, Yano Y, Perttula K, Whitehead T, Metayer C, Wheelock CE, Arora M, Grigoryan H, Carlsson H, Dudoit S, Rappaport SM. Metabolomics of neonatal blood spots reveal distinct phenotypes of pediatric acute lymphoblastic leukemia and potential effects of early-life nutrition. Cancer Lett. 2019 Jun 28;452:71-78. doi: 10.1016/j.canlet.2019.03.007. Epub 2019 Mar 20.

Schiffman C, Petrick L, Perttula K, Yano Y, Carlsson H, Whitehead T, Metayer C, Hayes J, Rappaport S, Dudoit S. Filtering procedures for untargeted LC-MS metabolomics data. BMC Bioinformatics. 2019 Jun 14;20(1):334. doi: 10.1186/s12859-019-2871-9

Yano Y, Grigoryan H, Schiffman C, Edmands W, Petrick L, Hall K, Whitehead T, Metayer C, Dudoit S, Rappaport S. Untargeted adductomics of Cys34 modifications to human serum albumin in newborn dried blood spots. Anal Bioanal Chem. 2019 Apr;411(11):2351-2362. doi: 10.1007/s00216-019-01675-8. Epub 2019 Feb 19


Perttula K, Schiffman C, Edmands WMB, Petrick L, Grigoryan H, Cai X, Gunter MJ, Naccarati A, Polidoro S, Dudoit S, Vineis P, Rappaport SM. Untargeted lipidomic features associated with colorectal cancer in a prospective cohort. BMC Cancer. 2018 Oct 19;18(1):996. doi: 10.1186/s12885-018-4894-4



Edmands WM, Petrick L, Barupal DK, Scalbert A, Wilson MJ, Wickliffe JK, Rappaport SM. compMS2Miner: An Automatable Metabolite Identification, Visualization, and Data-Sharing R Package for High-Resolution LC-MS Data Sets. Anal Chem. 2017 Apr 4;89(7):3919-3928. doi: 10.1021/acs.analchem.6b02394. Epub 2017 Mar 27

Petrick L, Edmands W, Schiffman C, Grigoryan H, Perttula K, Yano Y, Dudoit S, Whitehead T, Metayer C, Rappaport S. An untargeted metabolomics method for archived newborn dried blood spots in epidemiologic studies. Metabolomics. 2017 Mar;13(3). doi: 10.1007/s11306-016-1153-z. Epub 2017 Feb 3.

Petrick L, Rosenblat M, Aviram M. In vitro effects of exogenous carbon monoxide on oxidative stress and lipid metabolism in macrophages. Toxicol Ind Health. 2016 Jul;32(7):1318-23. doi: 10.1177/0748233714558084.

Petrick L, Rosenblat M, Paland N, Aviram M. Silicon dioxide nanoparticles increase macrophage atherogenicity: Stimulation of cellular cytotoxicity, oxidative stress, and triglycerides accumulation. Environ Toxicol. 2016 Jun;31(6):713-23. doi: 10.1002/tox.22084. Epub 2014 Nov 28


Petrick LM, Sabach S, Dubowski Y. Degradation of VX surrogate profenofos on surfaces via in situ photo-oxidation. Environ Sci Technol. 2013 Aug 6;47(15):8751-8. doi: 10.1021/es4016537. Epub 2013 Jul 22

Petrick LM, Sleiman M, Dubowski Y, Gundel L, Destaillats H. Tobacco smoke aging in the presence of ozone: a room-sized chamber study. Atmospheric environment. 2013; 45(28):4959. doi: 10.1016/j.atmosenv.2011.05.076.


Petrick LM, Svidovsky A, Dubowski Y. Thirdhand smoke: heterogeneous oxidation of nicotine and secondary aerosol formation in the indoor environment. Environ Sci Technol. 2011 Jan 1;45(1):328-33. doi: 10.1021/es102060v. Epub 2010 Dec 8.


Petrick L, Destaillats H, Zouev I, Sabach S, Dubowski Y. Sorption, desorption, and surface oxidative fate of nicotine. Phys Chem Chem Phys. 2010 Sep 21;12(35):10356-64. doi: 10.1039/c002643c. Epub 2010 Jun 25.


Petrick L, Dubowski Y. Heterogeneous oxidation of squalene film by ozone under various indoor conditions. Indoor Air. 2009 Oct;19(5):381-91. doi: 10.1111/j.1600-0668.2009.00599.x. Epub 2009 Feb 13


Petrick L, Dubowski Y, Klas S, Lahav O. Stable incorporation of CO2+ into ferrite structure at ambient temperature: effect of operational parameters. Water, Air and Soil Pollution. 2008; 190:245. doi: 10.1007/s11270-007-9597-4


Petrick LM, Wilson TA, Ronald Fawcett W. High-performance liquid chromatography-ultraviolet-visible spectroscopy-electrospray ionization mass spectrometry method for acrylic and polyester forensic fiber dye analysis. J Forensic Sci. 2006 Jul;51(4):771-9. doi: 10.1111/j.1556-4029.2006.00155.x

Fok W, Hild D, Petrick LM, Obendorf S. Autoxidation of spin finishes. Textile Research Journal. 2006; 76(8):614. doi: 10.1177/0040517506067674

Petrick LM, Hild D, Obendorf S. Observations of soiling of Nylon 66. Textile Research Journal. 2006; 76(3):253. doi: 0.1177/0040517506061036

review articles

Barr DB, Kannan K, Cui Y, Merrill L, Petrick LM, Meeker JD, Fennell TR, Faustman EM. The use of dried blood spots for characterizing children's exposure to organic environmental chemicals. Environ Res. 2021 Apr;195:110796. doi: 10.1016/j.envres.2021.110796. Epub 2021 Jan 25. Review.

Petrick LM, Arora M, Niedzwiecki MM. Minimally Invasive Biospecimen Collection for Exposome Research in Children's Health. Curr Environ Health Rep. 2020 Sep;7(3):198-210. doi: 10.1007/s40572-020-00277-2. Review

Petrick LM, Uppal K, Funk WE. Metabolomics and adductomics of newborn bloodspots to retrospectively assess the early-life exposome. Curr Opin Pediatr. 2020 Apr;32(2):300-307. doi: 10.1097/MOP.0000000000000875. Review.

Petrick LM and Noam Shomron. AI/ML-driven advances in untargeted metabolomics and exposomics for biomedical applications. Cell Reports Physical Chemistry. Volume 3, Issue 7, 100978, July20, 2022. DOI:

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